[PDF.34xp] Gene Prioritization: Rationale, Methodologies and Algorithms (SpringerBriefs in Systems Biology)

Gene Prioritization: Rationale, Methodologies and Algorithms (SpringerBriefs in Systems Biology)

[PDF.cl48] Gene Prioritization: Rationale, Methodologies and Algorithms (SpringerBriefs in Systems Biology)

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 | #7708453 in Books |  2014-03-19 |  2014-03-19 | Original language:English | PDF # 1 |  9.25 x.19 x6.10l,.0 | File type: PDF | 66 pages

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Identifying causal genes underlying susceptibility to human disease is a problem of primary importance in the post-genomic era and in current biomedical research. Recently, there has been a paradigm shift of such gene-discovery efforts from rare, monogenic conditions to common “oligogenic” or “multifactorial” conditions such as asthma, diabetes, cancers and neurological disorders. These conditions are referred to as multifactorial because, suscept...

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